Remember not to use air-Duster. Because it can blow dust in and around the unit, more critically on Blu-ray laser. This will worsen the situation.
2) Reset the PS3 defaults. First, turn off the PS3, turn it off, and then again after twenty minutes.
3) Format your hard disk. Many people who have a PS3 drive read problem reports after the new firmware update. Probably something in the new update screws up Blu-ray decoder and driver. So, you can reformat the hard disk. However, unfortunately this will cause you to lose all your data unless you back to the flash drive.
4) Send the PS3 back to Sony. I suggest you return it to Sony, if you still have warranty. If you are lucky enough, you May get a new replacement PS3.
5) Follow the PS3 repair manual and fix ps3 disc problem alone. If your warranty is over and the advice above does not work for you, try to find a good repair guide and fix it yourself. With the help of well-written manual, most players will play your favorite games again within 1 or 2 hours.